Perioperative protective effects of statins
نویسندگان
چکیده
منابع مشابه
Perioperative protective effects of statins
Although statins decrease cholesterol synthesis, they also possess 'pleiotropic' effects, such as enhancing the function of vascular endothelium and the stability of atherosclerotic plaques. Furthermore, they attenuate oxidative stress, inflammation, and the prothrombotic response. These diverse biological actions may explain their perioperative protective effects, especially in patients underg...
متن کاملthe perioperative effects of statins in non cardiac surgeries
background: statins (3-hydroxy-3-methylglutarylcoenzyme-a (hmg-coa) reductase inhibitors) decrease cardiovascular mortality and morbidity. this article reviews the role of perioperative statins in non cardiac surgery. methods: a literature review was done on all english published articles till february 2015 about this subject using pubmed. then the reference list of relevant articles was review...
متن کاملBeneficial effects of statins on perioperative cardiovascular outcome.
PURPOSE OF REVIEW This review evaluates clinical and experimental articles that have recently been published on the cardioprotective effect of perioperative statin therapy. RECENT FINDINGS Perioperative statin therapy improves short and long-term cardiac outcome following noncardiac surgery. This cardiovascular protection has been attributed to the so-called pleiotropic effects, which have a ...
متن کاملPerioperative use of statins in noncardiac surgery
BACKGROUND Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) can significantly decrease cardiovascular mortality and morbidity, irrespective of the patients' cholesterol status. This paper reviews the effects of perioperative statin therapy in patients undergoing noncardiac surgery. METHOD A systematic literature review was undertaken of all published literature on this sub...
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The traditional intraoperative ventilatory settings (tidal volume > 10 ml/kg ideal body weight) can be harmful even in patients with healthy lungs. In the operating theatre, safe anesthesia and optimization of oxygen delivery should be achieved while minimizing the deleterious effects of surgical trauma and avoiding iatrogenic complications. This review examines the mechanisms of perioperative ...
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ژورنال
عنوان ژورنال: F1000 Medicine Reports
سال: 2010
ISSN: 1757-5931
DOI: 10.3410/m2-35